Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis
Radwan, N., Nasr, M., Ishak, R., Awad, G. (2020). Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis. EKB Journal Management System, 4(1), 1-19. doi: 10.21608/APS.2020.2001.1021
Noha Hesham Radwan; Maha Sayed Nasr; Rania Aziz Ishak; Gehanne Awad. "Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis". EKB Journal Management System, 4, 1, 2020, 1-19. doi: 10.21608/APS.2020.2001.1021
Radwan, N., Nasr, M., Ishak, R., Awad, G. (2020). 'Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis', EKB Journal Management System, 4(1), pp. 1-19. doi: 10.21608/APS.2020.2001.1021
Radwan, N., Nasr, M., Ishak, R., Awad, G. Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis. EKB Journal Management System, 2020; 4(1): 1-19. doi: 10.21608/APS.2020.2001.1021

Recent Trends in the Use of Bioceramics for Treatment of Osteomyelitis

Archives of Pharmaceutical Sciences Ain Shams University
Article 1, Volume 4, Issue 1, June 2020, Page 1-19  XML PDF (709.03 K)
Document Type: Review Article
DOI: 10.21608/APS.2020.2001.1021
View on SCiNiTO View on SCiNiTO
Authors
Noha Hesham Radwan email 1; Maha Sayed Nasr2; Rania Aziz Ishakorcid 1; Gehanne Awad1
1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt
2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Abstract
Despite the inherent ability of bone for self-repair, this spontaneous healing capability in some bone disorders is not sufficient. Diseases as osteomyelitis, osteosarcoma, and osteoporosis, usually demand medical and/or surgical interventions to enhance tissue regeneration, control infection or to handle the clinical condition. Osteomyelitis (OM) is a bone infection disease, where Staphylococcus (S.) aureus is the main causative microorganism. OM is characterized by elevated rates of relapse and mortality. Coupling local osseous delivery of antibacterial agents with bioactive agents capable of bone regeneration was intensely studied for the treatment of OM, proving their effectiveness. Bioceramics are widely investigated due to their osteoconductive and osteointegration nature. Among these are calcium phosphates (CP), which are distinguished by a similar structure to that of bones and diverse resorption rates. CP is applied in the bone regeneration field, either solely or as composites with different polymers, as scaffolds, pastes, cement, and hydrogels. In this review we overview OM disease with its pathogenesis and treatment, especially focusing on different CP-bioceramics used for bone repair.
Keywords
Osteomyelitis; Calcium phosphate; Bioceramics; Scaffolds; Composites
Statistics
Article View: 772
PDF Download: 697