Leser-Trélat syndrome associated with cancer larynx : A case report

Ahmed, Mohammed; Ahmed, Mona; Abdelfattah, Hesham; Abu El-Hamd, Mohammed; Amr, Wael

doi:10.21608/ejentas.2018.10295

	Leser-Trélat syndrome associated with cancer larynx : A case report
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 6, Volume 19, Issue 1, March 2018, Page 21-23 PDF (587.46 K)
Document Type: Case report
DOI: 10.21608/ejentas.2018.10295
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Authors
Mohammed Ahmed ¹; Mona Ahmed ²; Hesham Abdelfattah³; Mohammed Abu El-Hamd⁴; Wael Amr⁵
¹Phoniatrics, Otorhinolaryngology-Head and Neck Surgery Department, Sohag University, Sohag, Egypt
²General Otolaryngology Phoniatrics, Otorhinolaryngology-Head and Neck Surgery Department, Sohag University, Sohag, Egypt
³Otorhinolaryngology-Head and Neck Surgery Department, University of Alexandria, Alexandria, Egypt
⁴Dermatology, Venereology and Andrology Department, Faculty of Medicine, Sohag University
⁵Surgery Department, Sohag Cancer Center, Sohag, Egypt
Abstract
Leser-Trélat syndrome (LTS) is a rare cutaneous paraneoplastic syndrome that barely affects patients with head and neck cancer. Here we present a case of 58-years old male presented with skin manifestation consistent with a sign of Leser-Trélat. A close investigation of the patient revealed that he had a recurrent laryngeal squamous cell carcinoma. The described case is the fifth case of a Leser-Trélat syndrome with squamous cell carcinoma of the larynx and the sixth to be reported in the head and neck squamous cell carcinoma. Thus sudden development of paraneoplastic dermatoses is recurrently a forewarning progression of the malignancy.


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