Leptin Values in Maternal and Umbilical Cord Blood in Pregnant Women with Preeclampsia | ||
| The Egyptian Journal of Fertility and Sterility | ||
| Article 2, Volume 23, Issue 2 - Serial Number 11106352, June 2019, Pages 11-17 PDF (1.92 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/egyfs.2019.105422 | ||
| Author | ||
| Elham Hussien Madny | ||
| Department of Obstetrics and Gynecology, Suez Canal University,Egypt | ||
| Abstract | ||
| Background: Leptin is a protein product of obesity gene and is syn- thesized mainly by adipose tissue. Objective: The aim of this study was to determine maternal and neo- natal serum leptin levels in preeclamptic and normal pregnancies. Patient and Methods: This corss sectional study was performed on 45 preeclamptic and 45 normotensive pregnant women without other disease.Serum level of leptin was measured in all of pregnant moth- ers and after delivery,measured in umbilical cord of their neonates. This study was performed in Hospitals of Suez Canal University. Results: In this study, when comparing the serum leptin levels be- tween normal pregnancies and pregnancies complicated with both mild and sever preeclampsia there was a highly statistically signif- icant deference in between (p< 0.01). plasmaleptin concentrations were significantly greater in women with pre-eclampsia than in nor- mal controls.Umbilical cord leptin concentrations were significantly greater in women with pre-eclampsia than in normal controls. Cord blood leptin in the present study showed that there is significant pos- itive correlation with severity of pre-eclampsia. Conclusion: According to the results, we detected an increase in ma- ternal plasma and umbilical cord leptin in preeclamticgroup.There was a highly statistically significant deference in between preeclam- tic group and the matched control group | ||
| Full Text | ||
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Leptin, Pre-eclampsia, Umbilical Cord | ||
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