SYNTHESIS AND FUNGICIDAL ACTIVITY OF NEW THIAZOLE DERIVATIVES WERE PREPARED FROM 2-BROMO-1-(3,4-DIMETHYLPHENYL)ETHANONE | ||
| Al-Azhar Bulletin of Science | ||
| Article 11, Volume 2008, Issue 12, December 2008, Pages 147-160 PDF (295.07 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/absb.2008.10820 | ||
| Authors | ||
| MAHMOUD S. BASHANDY* 1; MAHMOUD M. ABDELALL1; AHMED M. EL-MORSY2 | ||
| 1Chemistry Department Faculty of Science (Boy's), Al-Azhar University Nasr-City Cairo Egypt | ||
| 2Organic Chemistry Department Faculty of pharmacy (Boy's), Al-Azhar University Nasr-City Egypt | ||
| Abstract | ||
| 2-bromo-1-(3,4-dimethylphenyl)ethanone (2) was prepared and converted to thiazole derivatives (6-11a-c, 14-20) through reactions with different reagents. Compounds (3, 5, 12, 13, 21) were prepared from reaction of compound (2) with 2-mercapto-4,6-dimethylnicotinonitrile1H-benzo[d]imidazole-2-thiol, p-chloroaniline, potassium cyanide and 2-aminobenzenethiol respectively. The synthesized compounds were confirmed by elemental analysis, IR, 1H-NMR and mass spectral analysis. | ||
| Keywords | ||
| 2-bromo-1-phenylethanone; benzo[b][1, 4]thiazine; thiazole; 2-aminothiazole; 2-methylthiazole; 2H-chromen-2-one | ||
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