STUDY ON THIAZOLOPYRIDINES PART (7) : SYNTHESIS OF NOVEL THIAZOLIDINONE AND THIAZOLO[3,2-A]PYRIDINE DERIVATIVES | ||
| Al-Azhar Bulletin of Science | ||
| Article 14, Volume 2008, Issue 12, December 2008, Pages 193-199 PDF (326.53 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/absb.2008.10835 | ||
| Authors | ||
| GAMEEL A. ELHAG ALI* 1; HESSEN A. ALTAMAMY2; SHAABAN I. MOHAMED3; ZAMZAM A. BASHER2 | ||
| 1Department of Chemistry, Faculty of science, Al-Azhar University, Cairo, Egypt | ||
| 2Department of Chemistry, Faculty of science, Sebha University, Sebha, Libya | ||
| 3Technology Engineering Institute, Tamooh , Giza | ||
| Abstract | ||
| A novel 2-ethoxycarbonyl methylidine-4,5-dihydo-4-oxo-5-arylmethylidine-1,3-thiazole derivatives (2a-c) are obtained via the reaction of 4-thiazolinone derivative (1) with different aromatic aldehydes. Cyclization of 4-thiazolidinone derivatives (2a-c) with various α–cyanocinnamonitriles afforded the corresponding thiazolopyridine derivatives (5a-r). Thiazolopyridine derivatives (5a,b ) are refluxed with acetic anhydride, and gave N,N-diacetyl amino derivatives (8a,b). | ||
| Keywords | ||
| THIAZOLOPYRIDINES; pyridine derivatives | ||
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