APPLYING THE CONSERVATION OF MASS PRINCIPLE FOR THE INTERNAL VALIDATION OF FLOW MEASUREMENTS IN CARDIOVASCULAR MAGNETIC RESONANCE IMAGING | ||||
| Journal of the Medical Research Institute | ||||
| Article 3, Volume 40, Issue 1, August 2019, Page 32-35 PDF (454 K) | ||||
| DOI: 10.21608/jmalexu.2019.108592 | ||||
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| Abstract | ||||
| Background: Flow quantification is a central component in the evaluation of structural heart disease. Given the acoustic limitations of echocardiography, two-dimensional phase contrast magnetic resonance imaging (MRI) may be needed for non-invasive flow quantification. Careful evaluation of the dataset is necessary to ensure that the flow measurements are reliable. Aim: The aim of this study was to use the conservation of mass principle to check the validity of the flow measurements. Methods: Twenty consecutive patients referred cardiac MRI were included. Scans were acquired using a standard cardiac 1.5 Tesla MRI scanner. Phase-contrast MRI flow acquisition was planned in the proximal main pulmonary artery (MPA) and in the ascending aorta (Asc Ao). Results: Net flow in the MPA was 75 ± 17 ml and net aortic flow was 74 ± 18 ml (P = 0.565). Bland-Altman analysis showed a mean difference between measurements of 1.45 ± 11.0 ml. Conclusion: Applying the conservation of mass principle to check the internal validity of flow data is feasible and serves as a quality control measure for cardiac MRI. | ||||
| Keywords | ||||
| Glomerular conservation of mass; magnetic resonance imaging; flow quantification | ||||
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