SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY | ||
| Al-Azhar Bulletin of Science | ||
| Article 5, Volume 2006, Issue 6, June 2006, Pages 65-75 PDF (370.32 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/absb.2006.11640 | ||
| Authors | ||
| J. A. MICKY* ; N. M. SALEH; N. M. SHEMISS; S. A. MOHAMED | ||
| Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt. | ||
| Abstract | ||
| Interaction of 2-[1-(4,6-dimethoxybenzofuran-5-yl)ethylidine]malononitrile (1) with phenylisocyanate, phenylhydrazine, carbon disulphide and arylidenemalono-nitrile afforded the corresponding pyridine 2, pyrido[2,3-d] pyrimidine 3, phenylhydrazone 4,pyridine 2,6-dithione 8 and benzene dicarbonitrile 9 derivatives . Treatment of 1 with elemental sulfur under Gewald reaction conditions furnished 2-amino-4-(4,6-dimethoxybenzofuran-5-yl)thiophen-3-carbonitrile 11 which used as starting material in the synthesis of thienopyrimidine 14 and thienopyridine 15 derivatives. | ||
| Keywords | ||
| Pyridine; THIOPHENE; THIENOPYRIMIDINE; THIENOPYRIDINE; BENZOFURANYL | ||
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