Comparison between Cabergoline and Coasting in Prevention of Ovarian Hyperstimulation Syndrome and their effect on Intracytoplasmic Sperm Injection Outcome | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 7, Volume 73, Issue 1, October 2018, Pages 5753-5769 PDF (491.84 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2018.11877 | ||
| Authors | ||
| Ismaeil M. El-Garhy; Ahmed O. Abdel Motaal; Mohamed G. Omr* | ||
| Department of Obstetrics and Gynecology, Faculty of Medicine, Al Azhar University | ||
| Abstract | ||
| Aim of the work: ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, serious and potentially fatal complication of ovarian stimulation, affecting1–14% of all IVF/ICSI cycles. This study aimed to compare cabergoline after hCG administration with delayed hCG administration (coasting) in high risk patients to prevent OHSS in ART cycles. Patients and methods: this prospective comparative randomized study included 100 patients at risk of OHSS performed in the Assisted Reproductive Technologies Center, Al-Azhar University and in Private IVF Centers during the period from November, 2015 to October, 2016. Results: comparison between the two groups showed no significant difference regarding age, BMI, presence of risk factors of OHSS, but there was a significant difference regarding FSH, LH and the mean diameter of follicles on day of hCG administration. Conclusion: PCOS affects 5 to 10% of women of childbearing age and is the most common cause of anovulatory infertility in developed countries. Recommendations: further studies including large number of cases and for longer duration will further confirm the efficacy of cabergoline and coasting on prevention of OHSS. | ||
| Keywords | ||
| Cabergoline; Coasting; ovarian hyperstimulation syndrome; Intracytoplasmic Sperm Injection Outcome | ||
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