LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract | ||
| Egyptian Journal of Chemistry | ||
| Article 7, Volume 62, Issue 1, January 2019, Pages 77-83 PDF (547.98 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2018.4828.1428 | ||
| Authors | ||
| Ahmed ElKhateeb* ; Sameh Hussein; Maha Salem; Sabry El Negoumy | ||
| National Research Center | ||
| Abstract | ||
| Twenty one compounds (twelve flavonoids, four benzoylglucarate isomers, two phenolic acids, two glucosinolates, and one saccharide) were identified from the B. senegalensis aqueous methanolic extract using LC-ESI-MS technique. Among the identified compounds, quercetin-O-sinapoylglucoside-O-glucoside (13) and quercetin-di-O-benzoyl glucoside (16) are newly identified natural products. B. senegalensis aqueous methanolic extract showed strong inhibitory effect against H5N1 viruses and moderate antitumor activity against three carcinoma cell lines. | ||
| Keywords | ||
| Boscia senegalensis; Capparaceae; LC-ESI-MS; antitumor; Antiviral | ||
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