Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 11, Volume 69, Issue 6, October 2017, Pages 2627-2631 PDF (191.24 K) | ||
| Document Type: Original Article | ||
| DOI: 10.12816/0042239 | ||
| Authors | ||
| Marah Mohammed Alzaidi* 1; Hassan Hamza A Almir2; Afraa Qasim Ibrahim Khormi3; Yassmeen Mohammed Alltaleb4; Zahra Mohamed A Al Muwais5; Rehab Abdul Rahman Alsaleh6; Nora Faisal Alsaud7; Lama Mohammed Alomar8; Reema Adnan Shabkah9; Abdulrahman Hassan Khormi10; Reyhana Safi11 | ||
| 1Department of Obstetrics and Gynecology, Taif University, Taif | ||
| 2Department of Obstetrics and Gynecology Imam Abdulrahman bin Faisal university, Dammam | ||
| 3Department of Obstetrics and Gynecology, Jazan University, Jazan | ||
| 4Department of Obstetrics and Gynecology, Alfaisal University, Riyadh | ||
| 5Department of Obstetrics and Gynecology, Imam Abdulrahman bin Faisal university, Dammam | ||
| 6Department of Obstetrics and Gynecology, Ibn Sina National College, Jeddah | ||
| 7Department of Obstetrics and Gynecology, Alfaisal University | ||
| 8Department of Obstetrics and Gynecology, Almaarefa College for Science and Technology, Riyadh | ||
| 9Department of Obstetrics and Gynecology,King Abdulaziz University, Jeddah | ||
| 10Department of Obstetrics and Gynecology,king Fahd Central Hospital, Jazan, Saudi Arabia | ||
| 11Department of Obstetrics and Gynecology,Ibn Sina National College, Jeddah | ||
| Abstract | ||
| Over the past few decades, vitamin D was proposed to be highly influential on female fertility and reproductive health. Its role was extensively studied and evaluated specifically in females with polycystic ovarian syndrome. Objectives: the aim of this research was to study the correlation between vitamin D and fertility in general, and in polycystic ovarian syndrome-associated infertility in particular. Methods: we searched Cochrane Library and PubMed for articles addressing the impact and role of vitamin D in fertility issues in females with polycystic ovary disease. Specifically-related topics were carefully reviewed and analyzed to summarize their conclusive results. Results and Discussion: Vitamin D was lower in females with PCOS and vitamin D administration had increased its level, improved metabolic disturbance and shortened inter-menstrual intervals in those patients. Patients with high vitamin D levels had a better success rate of in-vitro fertilization. However, it did not affect the time to pregnancy in PCOS women. Conclusion: Vitamin D is beneficial for improving metabolic as well as reproductive functions in women with PCOS. It is also essential for successful in-vitro fertilization, and it is probably protective against endometriosis. However, results from different studies are contradictory, and still there is no solid evidence that there is a cause-effect relationship between vitamin D and fertility. | ||
| Keywords | ||
| polycystic ovary; PCO; Vitamin D; fertility | ||
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