Staphylococcus aureus nasal colonization among health care workers at an Egyptian tertiary care hospital

Allam, Ayman Abd Elrahman; Fakhr, Ahmed Elsadek; Mahmoud, Mai Essam; El-Korashi, Lobna Abdelaziz

doi:10.21608/mid.2020.52756.1095

	Staphylococcus aureus nasal colonization among health care workers at an Egyptian tertiary care hospital
Microbes and Infectious Diseases
Article 17, Volume 2, Issue 1, February 2021, Page 108-118 PDF (408.15 K)
Document Type: Original Article
DOI: 10.21608/mid.2020.52756.1095
View on SCiNiTO
Authors
Ayman Abd Elrahman Allam¹; Ahmed Elsadek Fakhr ²; Mai Essam Mahmoud³; Lobna Abdelaziz El-Korashi ¹
¹Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
²1 Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt 2 Pathology Laboratory and Blood Bank, International Medical Center, Jeddah, Saudi Arabia
³Department of infection control, Al-ahrar hospital, Zagazig, Egypt.
Abstract
Background: Staphylococcus aureus (S. aureus) colonization in health care workers (HCWs) is a major factor of nosocomial infections. Methicillin resistant S. aureus (MRSA) is incriminated in hospital-acquired infection. Objectives: To evaluate the colonization rates of nasal carriage of S. aureus and MRSA among HCWs at Al-Ahrar Teaching Hospital. Methods: We recruited 163 HCWs in a cross section study. S. aureus was identified phenotypically by coagulase, with DNase tests and genotypically by nuc gene detection. Antibiotics sensitivity was tested by disk diffusion. PCR for mecA was done to confirm MRSA identification. Results: Forty-eight S. aureus strain were isolated. The frequency of nasal colonization of S. aureus in HCWs was 29.44% (48/163), the frequency of MRSA isolates in HCWs was 27.6% (45/163), and frequency of MRSA isolates among S.aureus isolates was 93.8% (45/48). Prior infection (last 3 months) and living in crowded places increased significantly risk of MRSA nasal carriage by 29.3 and 79.59 folds respectively Conclusion: We demonstrated high rates of nasal carriage of S. aureus and MRSA among HCWs. Prior infection and living in crowded places were risk factors for methicillin resistance among isolated S.aureus stains.
Keywords
Staphylococcus aureus; resistance; MRSA; MSSA; health care worker


Statistics Article View: 1,170 PDF Download: 555