Behaviour of 4,6-Diaryl-2(1H) pyrimidine-2-thiones Towards Some Electrophiles and Nucleophiles | ||
Egyptian Journal of Chemistry | ||
Article 2, Volume 54, Issue 1, February 2012, Pages 17-34 PDF (481 K) | ||
DOI: 10.21608/ejchem.2011.1377 | ||
Abstract | ||
4,6-DIARYl-1,2-dihydro-2(1H)-pyrimidine-2-thiones (1a,b) were ….used for the synthesis of several new pyrimidine derivatives. They were further subjected to hetero ring anellation affording isoxazolo [4,5-d] thiazolo [2,3-a] pyrimidine (5,6) and isoxazolo [4,5-d] thiazino [2,3-a] pyrimidines (11,12) . Biological evaluation of some of the prepared compounds revealed promising antimicrobial activity. | ||
Keywords | ||
Pyrimidinethione; Pyrimidothiazine; Thiazolopyrimidine and Antimicrobial activity | ||
Statistics Article View: 396 PDF Download: 611 |