Saponin ameliorate diabetes in STZ-diabetic rats | ||
| Delta Journal of Science | ||
| Article 5, Volume 38, Issue 2, December 2017, Pages 177-182 PDF (966.18 K) | ||
| Document Type: Research and Reference | ||
| DOI: 10.21608/djs.2017.139442 | ||
| Authors | ||
| Amira Ragab El Barky1; Samy A. Hussein2; Abeer A. Alm-Eldeen3; yehia A. Hafez4; Tarek M. Mohammed* 1 | ||
| 1Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt | ||
| 2Biochemistry Department, Faculty of Veterinary medicine, Benha University, Benha, Egypt | ||
| 3Zoology Department, Faculty of Science, Tanta University, Tanta, Egypt | ||
| 4Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt | ||
| Abstract | ||
| Saponins exhibit a wide spectrum of biological activities. Hyperglycemia was induced by STZ. Saponin extract(300 mg/kg B.wt.) was administrated to STZdiabetic rats. Saponin extract significantly reduced serum blood glucose, cholesterol, triacylglycerol, liver L-MDA and significantly increased serum insulin level, In conclusion, saponin has antidiabetic effect on STZ- diabetic rats. | ||
| Keywords | ||
| Streptozotocin; Diabetes; oxidative stress; Saponin | ||
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