Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis
(2011). Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis. EKB Journal Management System, 54(3), 299-312. doi: 10.21608/ejchem.2011.1396
. "Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis". EKB Journal Management System, 54, 3, 2011, 299-312. doi: 10.21608/ejchem.2011.1396
(2011). 'Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis', EKB Journal Management System, 54(3), pp. 299-312. doi: 10.21608/ejchem.2011.1396
Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis. EKB Journal Management System, 2011; 54(3): 299-312. doi: 10.21608/ejchem.2011.1396

Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis

Egyptian Journal of Chemistry
Article 1, Volume 54, Issue 3, June 2012, Pages 299-312    PDF (416.03 K)
DOI: 10.21608/ejchem.2011.1396
Abstract
THE PRESENT work deals with the generation and synthesis of different unnatural amino acid derivatives via treatment of 3-(4-acetamidobenzoyl)-prop-2-enoic acid with 5-aryl-2- amino 1, 3, 4 thiadiazole, 3, 5-dimethyl pyrazole and barbituric acid to afford the product of conjugate addition acids (1) respectively. Additionally, the adduct 1 are used as key starting materials to synthesize some heterocycles include pyridazene , furanone and oxazine derivatives. The antimicrobial screening of some of the synthesized compounds was done using the agar diffusion assay
Keywords
3-Acetamidobenzoyl prop-2-enoic acid; Pyrazole thiadiazole; Phthalimide; Barbituric acid; furanone; Pyridazine and Oxazine
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