Synthesis and Antitumor Activity Evaluation of New 2-(4-aminophenyl) benzothiazole/oxazole/imidazole Derivatives | ||
| Egyptian Journal of Chemistry | ||
| Article 3, Volume 59, Issue 6, December 2016, Pages 967-984 PDF (743.15 K) | ||
| DOI: 10.21608/ejchem.2016.1544 | ||
| Abstract | ||
| A NEW series of 2-(4-aminophenyl)benzothiazole and related structure compounds, bearing thiocyanate, thiol in the 3'postion as well as new condensed benzothiazoles and related structure compounds having thiazolones ,tetrazole, oxadiazole have been synthesized . All the newly synthesized compounds were screened for their anti-tumor activities. The results revealed promising effects against most of the cancer cell lines. | ||
| Keywords | ||
| 2-(4 aminophenyl) benzothiazole/ benzoxazole/ benzimidazole; Tetrazole; Oxadiazole; thiazole; Oxobutanoate; Tolyiformamidine; Chlorophenyl-formamidine; anticancer agent | ||
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