SYNTHESIS AND PHARMACOLOGICAL SCREENING OF CERTAIN IMIDAZOQUINAZOLONE DERIVATIVES | ||
Bulletin of Pharmaceutical Sciences Assiut University | ||
Article 2, Volume 31, Issue 1, June 2008, Pages 29-48 PDF (393.51 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/bfsa.2008.156596 | ||
Authors | ||
Fatma A. Ragab; Hassanein H. Hassanein; Enayat I. Ali; Hanan H. Georgey | ||
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Egypt | ||
Abstract | ||
Certain imidazoquinazolin-5(4H)-one derivatives have been synthesized by replacement of the 4-amino group compound I with different moieties of expected biological activity. Representative example of the synthesized compounds were tested for their anti-inflammatory, analgesic, antipyretic and anticonvulsant activities. Certain derivatives showed activities higher than that of the reference drugs. | ||
Statistics Article View: 116 PDF Download: 185 |