Effect of green tea consumption on level of glucose, lipid profile and kidney functions in alloxan induced-diabetic rats | ||||
| Egyptian Academic Journal of Biological Sciences. A, Entomology | ||||
| Article 11, Volume 1, Issue 2, December 2008, Page 125-134 PDF (204.34 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/eajbsa.2008.15744 | ||||
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| Authors | ||||
| Abd-Elraheim A. Elshater; Muhammad M. A. Salman; Mahrous M. A. Moussa | ||||
| South Valley University, Faculty of Science, Zoology Department, Qena | ||||
| Abstract | ||||
| In recent years, green tea has become a subject of interest because of its beneficial effects on human health. The purpose of the present study was to investigate the effects of daily oral administration of green tea extract for 6 weeks on plasma glucose, lipid profile and kidney functions in alloxan-induced diabetic rats to show the preventive and curative effects of green tea. Rats (130-150 g) were divided into 4 groups, normal control rats, diabetic rats, diabetic rats post-treated with green tea and diabetic rats pretreated with green tea. Green tea extract was administered orally for 6 weeks to the third and forth groups (300 mg/kg b.w,). Plasma glucose, triglycerides, HDL and LDL-cholesterol were significantly reduced in post-treated and pre-treated groups while plasma cholesterol was significantly reduced only in post-treated group while plasma creatinine, urea and uric acid levels were significantly reduced in post-treated diabetic group, but in the pre-treated group creatinine and uric acid levels were reduced, but urea level did not change. It is concluded that the consumption of green tea produced a significant reduction in glucose level in diabetic rats. In addition green tea is capable of improving hyperlipidaemia and the impaired kidney functions in addition to its hyperglycemic control. | ||||
| Keywords | ||||
| green tea; plasma; diabetic rats; lipids; glucose; urea; creatinine; Uric acid | ||||
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