Predictors of Malignancy in Thyroid Nodules | ||||
| International Journal of Medical Arts | ||||
| Article 26, Volume 3, Issue 2, April 2021, Page 1369-1376 PDF (1.17 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2021.43700.1178 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Abdel Rahman Ahmed Mohamed Ragab  ; Ahmed Salama Sayouh; Amr Abdel Ghany Sarhan
| ||||
| Department of Surgery, Damietta Faculty of Medicine, Al-Azhar University, Egypt | ||||
| Abstract | ||||
| Background: Better and early prediction of malignant thyroid nodule, and sure differentiation from benign one, is crucial need to decrease the rate of non-indicated surgeries. The aim of the work: To find risk factors and predictors of malignancy in patients with thyroid nodule[s]. Patients and Methods:Fifty patients with thyroid nodule[s] were included. All patients were evaluated by history taking, clinical examination and laboratory investigations. Imaging studies included thyroid ultrasound [US]. All were also submitted to fine needle aspiration cytology [FNAC] before treatment by total or subtotal thyroidectomy. Excised tissues were sent to histopathological analysis. Results:The incidence of malignancy was 22.0%. both benign and malignant groups were comparable as patient characteristics, complaints except the significant increase in cosmetic disfigurement among patients with benign nodules [92.3% vs. 45.5%].Patients with malignant nodules had a significant increase of ill-defined margins, intranodular vascularity and enlarged lymph nodes [72.7%, 63.6% and 72.7% vs 5.1%, 12.8% and 25.6% respectively]. Ill-defined margins, enlarged lymph node and high grade in FNAC were the predictors of thyroid malignancy. Conclusion: Predictors of malignant thyroid nodules are ill- defined edges, enlarged lymph node and high grade in FNAC. This helps clinicians to spare more benign cases from surgical interference. | ||||
| Keywords | ||||
| Thyroid; Malignant; Benign; Ultrasound; Predictor | ||||
|
Statistics Article View: 476 PDF Download: 294 |
||||
