Assessment of Oral Cellular proliferative activity among Toombak Dipper in Al-Obeyed City, Sudan | ||
| Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology | ||
| Article 13, Volume 6, Issue 2, December 2014, Pages 107-113 PDF (540.45 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsc.2014.16037 | ||
| Authors | ||
| Awad Eljeed Abugooda Alobaid1; Ibrahim Bakhit Yousef Elemam1; Mohammed Abed Algader Alsheikh2; Abdalhafeez Osman Mahmud3; Hussain Gadelkarim Ahmed3 | ||
| 1Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan. | ||
| 2Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan | ||
| 3Department of Pathology, College of Medicine, University of Hail, KSA | ||
| Abstract | ||
| Background: Many factors have been identified as important causative agents that responsible for the development of oral precancerous and cancerous lesions. In Sudan, Toombak have been identified as a major risk factor. Therefore, the aim of this study was to assess the cellular proliferative activity that associated with Toombak use. Methodology: In this study 75 apparently healthy individuals were selected for this study, of whom 50 were currently Toombak users (cases) and 25 were non-Toombak users (controls), Pap. Method and Silver technique were used for the staining of oral smears. Results: Cytological atypia was identified in 10 cases and 4 controls. The mean count NORs count was 4.6 in cases and 2.2 in controls. Conclusion: Toombak is a major risk for occurrence of cellular proliferative activity features that may progress in to oral precancerous or cancerous lesions. | ||
| Keywords | ||
| Toombak; Cytological atypia; oral cancer; Al-Obeyed | ||
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