Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases
Gad, S., Desoqi, M., El-Sawy, H., Khafagy, E., Ghourab, M. (2021). Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases. EKB Journal Management System, 5(Pharmacology-Pharmaceutics), 59-64. doi: 10.21608/rpbs.2021.62807.1094
Shadeed Gad; Mohamed Desoqi; Hossam El-Sawy; Elsayed Khafagy; Mamdouh Ghourab. "Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases". EKB Journal Management System, 5, Pharmacology-Pharmaceutics, 2021, 59-64. doi: 10.21608/rpbs.2021.62807.1094
Gad, S., Desoqi, M., El-Sawy, H., Khafagy, E., Ghourab, M. (2021). 'Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases', EKB Journal Management System, 5(Pharmacology-Pharmaceutics), pp. 59-64. doi: 10.21608/rpbs.2021.62807.1094
Gad, S., Desoqi, M., El-Sawy, H., Khafagy, E., Ghourab, M. Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases. EKB Journal Management System, 2021; 5(Pharmacology-Pharmaceutics): 59-64. doi: 10.21608/rpbs.2021.62807.1094

Drug Delivery Systems for Topical treatment of Inflammatory Skin Diseases

Records of Pharmaceutical and Biomedical Sciences
Article 7, Volume 5, Pharmacology-Pharmaceutics, January 2021, Page 59-64  XML PDF (510.17 K)
Document Type: Mini-reviews
DOI: 10.21608/rpbs.2021.62807.1094
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Authors
Shadeed Gad email orcid 1; Mohamed Desoqi2; Hossam El-Sawy3; Elsayed Khafagy4; Mamdouh Ghourab5
1Faculty of Pharmacy - Suez Canal University
2Pharmacy Department, The Armed Forces Medical Complex, Qobry El Qoba, Ministry of Defense, Egypt
3Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt
4Dept. of Pharmaceutics Faculty of Pharmacy, Suez Canal University
5Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University
Abstract
The skin is known to be the primary intact skin layer for the application of cosmetics and medicines. These nanocarriers, however, can enhance the distribution of molecules through hair follicles or impart a regulated pattern of release by making depots on the skin.. moreover, Many challenges may potentially face the topical delivery of medicaments through either the healthy or diseased skin. This is mainly owing to the strong protection offered by the barriers made of the skin. This paper displays the blocking nature of the skin, the difficult conditions of skin inflammatory diseases, options of effective treatment, and general categories of advanced topical drug delivery for better efficacy and safety. Solid lipid nanoparticles and other lipid-based nanocarriers are mentioned particularly with a further focus along with examples of opportunities for bioavailability enhancement of poorly absorbed active moieties and for more promising implementation in convenient and efficient topical remediation of skin inflammatory disorders.
Keywords
Skin inflammatory diseases; Gluco-corticosteroids; Topical drug delivery systems; Solid lipid nanoparticles
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