SATHESIS AND ANTITICROBIALEVALUATI0N OF CERTAIN NEW 1,2,4-TRIAZOLE AND p-AMINOBENZOIC ACID DERIVATIVES | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 18, Issue 2, December 2009, Pages 1-7 PDF (1.8 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.2009.162493 | ||
| Authors | ||
| Mohamed Hussien* ; Ali Ahmdy | ||
| Pharmaceutical Chemistry and Microbiology Department faculty of Pharmacy ,Cairo University. Cairo, Egypt. | ||
| Abstract | ||
| Different types of mycoses especially invasive mycoses caused by yeasts and molds. are a growing problem in healthcare Candida albicans is one of the most common opportunistic fungi responsible for these kinds of infections the most notable explanation for this increase is a rise in the number of immunocompromised patients owing to advances in transplantation, the emergence of AIDS and rise m the number of invasive surgical procedures. Conveniently accessible hydrazide derivatives of benzoic acid 1 were converted to new thiosemicarbazides. Triazoles and alkylthiotriazoles. The antibacterial and antifungal activities were determined .Some of the newly synthesized compounds showed weak corresponding activities. | ||
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