The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress | ||
Alfarama Journal of Basic & Applied Sciences | ||
Article 5, Volume 2, Issue 2, July 2021, Pages 214-223 PDF (178.15 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/ajbas.2021.69350.1049 | ||
Authors | ||
Faten Zahran1; samia Hagag* 2; Osama Ramadan3; Hoda Abdallah4; Mohamed Gharib5 | ||
1Chemistry Department, Faculty of Science, Zagazig University, Egypt. | ||
2biochemistry, animal health research institute, Zagazig, Egypt | ||
3Pharmacology Department, Animal Health Research Institute, Egypt | ||
42 Biochemistry Department, Animal Health Research Institute, Agriculture research centre, Egypt. | ||
5Chemistry Department, Faculty of Science, Port-Said University, Port-Said, Egypt. | ||
Abstract | ||
In hot areas, heat stress (HS) is one of the most prominent stressors in the broiler industry. To provide comprehensive information about the effect of N-acetyl cysteine (NAC) on hamartiology, biochemistry, and thyroid hormones in broilers under thermoneutral (TN) (22 4 ° C) and heat stress (HS) (34 2 ° C), The current study was carried out. A total of 80 one-day-old Cobb broiler chicks were used, with 20 birds in each group receiving either a control (basal diet) or a NAC (100 mg/Kg diet). Chronic HS at 42 days resulted in a considerable decrease in HGB, PCV, RBCs, total protein, Albumin, serum T3 and T4, while greatly increasing H/L, triglycerides, cholesterol, LDL-cholesterol, uric acid, AST, ALT, ALP, TBIL, DBIL, and creatinine. When compared to HSC broilers at 42 d old, NAC supplementation greatly increased PCV content with a substantial decrease in total leukocytic count, heterophils, and H/L ratio with an increase in lymphocytes and monocytes. When compared to HSC population, chickens given NAC had a significant decrease in serum AST, ALP, ALT and triglyceride levels, as well as a significant increase in serum T3 concentration. | ||
Keywords | ||
Heat stress; Thermoneutral; Broiler chickens; NAC; N-acetyl cysteine | ||
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