The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress
Zahran, F., Hagag, S., Ramadan, O., Abdallah, H., Gharib, M. (2021). The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress. EKB Journal Management System, 2(2), 214-223. doi: 10.21608/ajbas.2021.69350.1049
Faten Zahran; samia Hagag; Osama Ramadan; Hoda Abdallah; Mohamed Gharib. "The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress". EKB Journal Management System, 2, 2, 2021, 214-223. doi: 10.21608/ajbas.2021.69350.1049
Zahran, F., Hagag, S., Ramadan, O., Abdallah, H., Gharib, M. (2021). 'The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress', EKB Journal Management System, 2(2), pp. 214-223. doi: 10.21608/ajbas.2021.69350.1049
Zahran, F., Hagag, S., Ramadan, O., Abdallah, H., Gharib, M. The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress. EKB Journal Management System, 2021; 2(2): 214-223. doi: 10.21608/ajbas.2021.69350.1049

The Protective Role of N-Acetyl Cysteine (Nac) on Broilers Exposed to Chronic Heat Stress

Alfarama Journal of Basic & Applied Sciences
Article 5, Volume 2, Issue 2, July 2021, Pages 214-223    PDF (178.15 K)
Document Type: Original Article
DOI: 10.21608/ajbas.2021.69350.1049
Authors
Faten Zahran1; samia Hagag* 2; Osama Ramadan3; Hoda Abdallah4; Mohamed Gharib5
1Chemistry Department, Faculty of Science, Zagazig University, Egypt.
2biochemistry, animal health research institute, Zagazig, Egypt
3Pharmacology Department, Animal Health Research Institute, Egypt
42 Biochemistry Department, Animal Health Research Institute, Agriculture research centre, Egypt.
5Chemistry Department, Faculty of Science, Port-Said University, Port-Said, Egypt.
Abstract
In hot areas, heat stress (HS) is one of the most prominent stressors in the broiler industry. To provide comprehensive information about the effect of N-acetyl cysteine (NAC) on hamartiology, biochemistry, and thyroid hormones in broilers under thermoneutral (TN) (22 4 ° C) and heat stress (HS) (34 2 ° C), The current study was carried out. A total of 80 one-day-old Cobb broiler chicks were used, with 20 birds in each group receiving either a control (basal diet) or a NAC (100 mg/Kg diet). Chronic HS at 42 days resulted in a considerable decrease in HGB, PCV, RBCs, total protein, Albumin, serum T3 and T4, while greatly increasing H/L, triglycerides, cholesterol, LDL-cholesterol, uric acid, AST, ALT, ALP, TBIL, DBIL, and creatinine. When compared to HSC broilers at 42 d old, NAC supplementation greatly increased PCV content with a substantial decrease in total leukocytic count, heterophils, and H/L ratio with an increase in lymphocytes and monocytes. When compared to HSC population, chickens given NAC had a significant decrease in serum AST, ALP, ALT and triglyceride levels, as well as a significant increase in serum T3 concentration.
Keywords
Heat stress; Thermoneutral; Broiler chickens; NAC; N-acetyl cysteine
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