Is Herpes Simplex Virus (HSV) infection a risk factor for nasopharyngeal carcinoma? | ||||
| Egyptian Academic Journal of Biological Sciences, G. Microbiology | ||||
| Article 4, Volume 6, Issue 2, December 2014, Page 27-32 PDF (280.52 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/eajbsg.2014.16496 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Hussain Gadel karim Ahmed1; Rania Saad Abdul Gader Suliman2; Mohammed Siddig Abd El Aziz2; Fawaz D. Alshammary3; Faris Margani Altom4; Ibrahim A Ginawi1 | ||||
| 1Department of Pathology, College of Medicine, Molecular Diagnostics and Personalized Therapeutics Unit, University of Hail, KSA; Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan | ||||
| 2Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan | ||||
| 3Department of Medical Laboratory Science, College of Applied Medical Science, University of Hail, KSA | ||||
| 4Department of Medical Laboratory Science, College of Applied Medical Science, University of Taibah, KSA | ||||
| Abstract | ||||
| Objective: The aim of this study was to screen for the presence of HSV in patients with nasopharyngeal Carcinoma (NPC). Methodology: Formalin fixed paraffin wax processed NPC tissue were obtained from 150 tissue blocks and retrospectively investigated for the presence of HSV-1 and HSV-2 using polymerase Chain Reaction (PCR). Results: Of the 150 NPC tissue specimens, Herpes Simplex Virus type 2 (HSV-2) was identified in 18/150 (12%) samples. Out of the 18 samples infected with HSV-2, 15/97 (15.5%) among males and 3/53(5.7%) were among females. Conclusion: The present have shown some weak links between HSV and NPC. The great majority of samples harboring HSV were also found to harbor EBV, which suggests the potentiality of EBV over HSV. | ||||
| Keywords | ||||
| Herpes Simples Virus; Nasopharyngeal carcinoma | ||||
|
Statistics Article View: 296 PDF Download: 362 |
||||
