Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base | ||
| Egyptian Journal of Chemistry | ||
| Article 24, Volume 64, Issue 8, August 2021, Pages 4191-4195 PDF (531.97 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.55320.3166 | ||
| Authors | ||
| C. VEERAVEL* 1; Rajasekar K2; Balasubramaniyan S3; R. SELVARANI1 | ||
| 1DEPARTMENT OF CHEMISTRY, GOVT ARTS COLLEGE, ARIYALUR-621713. TAMIL NADU, INDIA | ||
| 2Department of Chemistry, Govt Arts College, Ariyalur, Tamil Nadu, India | ||
| 3Department Of Chemistry, Govt Arts College, Tamil Nadu, India | ||
| Abstract | ||
| Abstract The first-row transition metal complex of Schiff base has been synthesized and characterized based on physicochemical spectral and biochemical methods. The metal-ligand stoichiometry and molecular formula of the complex assessed by Elemental analysis and metal estimation-neutral, monomeric nature of the complex and paramagnetic nature also predict by the conductance and magnetic moment study. The octahedral environment around Co(II) and metal-imine bond as a whole predicted by atomic IR and Far-IR spectra. In-vitro antibacterial and antifungal activities of the Schiff base and its complexes compared with those for standard (Chloramphenicol & Fluconazole) by agar disc diffusion method. The Ex-vivo antimalarial activity of the Schiff base and its metal complex was found by using Plasmodium falciparum bacteria/fungal. | ||
| Keywords | ||
| Keywords: Cinnamaldehyde; Aniline; ligand; Conductance; Chloramphenicol; and Fluconazole | ||
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