EVIDENCE OF ANTI-DOUBLE STRANDED DNA ANTIBODIES AND C-REACTIVE PROTEIN IN EGYPTIAN PATIENTS WITH HIGH ANTI-SCHISTOSOMA MANSONI ANTIBODY TITER | ||
| Journal of the Egyptian Society of Parasitology | ||
| Article 19, Volume 51, Issue 1, April 2021, Pages 147-152 PDF (769.88 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jesp.2021.165956 | ||
| Authors | ||
| HANAA O. FADL; MOUSA A. M. ISMAIL; ENAS A. EL SAFTAWY | ||
| Department of Medical Parasitology | ||
| Abstract | ||
| Schistosomiasis is one of the major public health diseases that induced a diversity of immunologic reactions. Significant association between autoreactive antibodies and autoimmune disorders was suggested. This study investigated the presence of anti-double stranded DNA (anti-ds DNA) antibodies and inflammatory biomarker, C-reactive protein (CRP) in 89 Egyptian patients, with Schistosoma mansoni clinical evidence and high anti-Schistosoma antibody titer. The results showed positive serum anti-ds DNA antibodies in 11/89(12.4%) of them, without significance to age, sex or anti-Schistosoma antibody titers. CRP was positive in 20/89(22.5%) of patients, with significant correlation with anti-ds DNA antibodies (P=0.000). | ||
| Keywords | ||
| Egypt; Schistosoma mansoni-anti-ds DNA- CRP- autoimmune disease | ||
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