PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.
Farah, H., Al- Atoom, A., Shehab, G., Abd El-wahab, M. (2011). PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.. EKB Journal Management System, 20(2), 24-36. doi: 10.21608/zjps.2011.167360
Husni Farah; Ali Al- Atoom; Gaber Shehab; Mohammed Abd El-wahab. "PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.". EKB Journal Management System, 20, 2, 2011, 24-36. doi: 10.21608/zjps.2011.167360
Farah, H., Al- Atoom, A., Shehab, G., Abd El-wahab, M. (2011). 'PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.', EKB Journal Management System, 20(2), pp. 24-36. doi: 10.21608/zjps.2011.167360
Farah, H., Al- Atoom, A., Shehab, G., Abd El-wahab, M. PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.. EKB Journal Management System, 2011; 20(2): 24-36. doi: 10.21608/zjps.2011.167360

PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.

Zagazig Journal of Pharmaceutical Sciences
Article 3, Volume 20, Issue 2, December 2011, Pages 24-36    PDF (3.06 M)
Document Type: Original Article
DOI: 10.21608/zjps.2011.167360
Authors
Husni Farah* 1; Ali Al- Atoom1; Gaber Shehab1; Mohammed Abd El-wahab* 2
1Department of Medical Biochemistry, College of Medicine, Taif University, KSA
2Pharmacognosy Department, Faculty of pharmacy, Al-Azhar University, Cairo, Egypt.
Abstract
Pharmacognostical studies on zizyphus lotus (L.) Lam; was carried out to identify and differentiate the plant organs. Phytochemical screening revealed that the plant rich with carbohydrates and/or glycosides, volatile substances, saponins, flavonoids, phenolics, steroids and/or triterpenes, and alkaloids and/or nitrogenous bases. The biological studies showed that 70% alcohol extract had promising antimicrobial activity. By examination of the LD50 and analgesic effect after oral administration of various doses of extract 100, 200 and 300 mg/kg body weight, the LD50 of 70% alcohol extract of Zizyphus lotus L. (Lam ) is 12.88 g /kg (mice) with confidence limit of 10.75 g /kg (mice) and 15.44 g /kg (mice). All tested extracts showed significant analgesic activity in all times of experiments except at 20 min. In conclusion.the tested extract can be used safely for analgesic purposes.
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