Effect of Some Slimming Drugs on Some Biochemical and Physiological Parameters of Albino Rats | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 2, Volume 35, Issue 1, April 2009, Page 246-253 PDF (769.27 K) | ||||
| DOI: 10.21608/ejhm.2009.17563 | ||||
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| Authors | ||||
| Eman G.E. Helal1; Ali A. Shati2; Fahmy G. Elsaid3 | ||||
| 1Zoology dep., Faculty of Science, Al-Azhar University, Egypt | ||||
| 2Life Science Dep., Faculty of Science, King Khalid University, KSA. | ||||
| 3Zoology Dep., Faculty of Science, Mansoura University, Egypt. | ||||
| Abstract | ||||
| Background:The slimming drugs differ in their nature, where apple-lite is a fully natural substance, mirapro-N is a chemical substance and tenuate is a synthetic foamy filler substance. The study aimed to search the physiological and biochemical changes accompanied with these drugs on rats. Methods:Forty adult male albino rats (130±20g) were divided into four groups, ten on each treated group and ten for the control one. The apple-lite group treated with 3.5mg/100 g body weight, the mirapro-N group treated with 0.14mg/100g body weight and the tenuate group treated with 0.1 mg/100 g body weight. Results: The treated groups showed a significant changes in the lipid and protein profiles, enzymatic activities, in the skin folds and the percentage of body weight compared to the control group. In conclusion, the slimming drugs showed a change in skin folds thickness and in percentage of organ’s weight to body weight and also showed a deflection in the investigated biochemical parameters. | ||||
| Keywords | ||||
| Slimming drugs; tenuate; apple-lite; mirapro-N; Lipid profile; liver function; skin folds | ||||
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