Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 9, Volume 33, Issue 1, October 2008, Pages 559-568 PDF (347.4 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2008.17618 | ||
| Author | ||
| Mohammed Salah Ab.Ab. AL-Shinnawy | ||
| Biological and Geological Sciences Department , Faculty of Education , Ain Shams University , Cairo , Egypt . | ||
| Abstract | ||
| Background:The current investigation was carried out to study the effect of orally administration of diazinon insecticide on some biochemical blood indices on male albino rats. Material and methods: The organophosphorus insecticide , diazinon was orally administrated at a dose (100mg/kg body weight=1/3LD50) , daily for 10 days (short –term) and 20 days (long –term) to adult male albino rats . Results: The results revealed the following: 1- Diazinon led to an increase in rat blood serum glucose& T3 (short and long –term); AST,ALT, and T4 (long-term). 2- Diazinon reduced the serum content of total cholesterol and protein in short–term treated rats. 3- Treatment of rats with diazinon did not alter activity of AST, ALT and T4 level at short –term period .In addition ; ALP serum levels were not altered in both short and long –term treated rats . | ||
| Keywords | ||
| Diazinon; Organophosphorus insecticide; Biochemical changes; serum | ||
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