CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OL OF ARAUCARIA EXCELSA R. Br. CULTIVATED IN EGYPT | ||
Zagazig Journal of Pharmaceutical Sciences | ||
Article 6, Volume 12, Issue 1, June 2003, Pages 36-43 PDF (3.46 M) | ||
Document Type: Original Article | ||
DOI: 10.21608/zjps.2003.178073 | ||
Author | ||
Afaf Abdel-Ghani* | ||
Department of Pharmacognosy, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt. | ||
Abstract | ||
The essential oil of leaves, stem bark and wood of Araucaria excelsa were prepared by hydrodistillation. Analysis of the oils by GC and GC-MS resulted in the identification of 78 compounds. The diterpene; phyllocladene (37.86%) is the major compound of leaves oil, while α-pinene (16.46%) and caryophyllene oxide (15.71%) are the major components of bark oil. The diterpenoids; kaurene, isopimarol and phyllocladanol are the major constituents of wood oil in relative percentage of 18.59%,12.09% and 10.73%, respectively. The major component of the leaves oil; phyllocladene was isolated and its structure was established by spectral data (UV, IR, MS, 1H- and 13C-NMR). All the prepared oils and phyllocladene exhibited marked antimicrobial and antifungal activities. | ||
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