Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis
Gohar, S., Hosny, M., Abdel-Hamid, H., Ibrahim, Y. (2006). Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis. EKB Journal Management System, 24(1), 430-441. doi: 10.21608/ejhm.2006.17907
Sabry Gohar; Mone Hosny; Howayda Abdel-Hamid; Yasser Ibrahim. "Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis". EKB Journal Management System, 24, 1, 2006, 430-441. doi: 10.21608/ejhm.2006.17907
Gohar, S., Hosny, M., Abdel-Hamid, H., Ibrahim, Y. (2006). 'Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis', EKB Journal Management System, 24(1), pp. 430-441. doi: 10.21608/ejhm.2006.17907
Gohar, S., Hosny, M., Abdel-Hamid, H., Ibrahim, Y. Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis. EKB Journal Management System, 2006; 24(1): 430-441. doi: 10.21608/ejhm.2006.17907

Non-fasting Non-High Density Lipoprotein Cholesterol (Non-HDL-C) AS A predictor of Atherosclerosis in Patients with End Stage Renal Disease on Regular Hemodialysis

The Egyptian Journal of Hospital Medicine
Article 3, Volume 24, Issue 1, July 2006, Pages 430-441    PDF (654.74 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2006.17907
Authors
Sabry Gohar1; Mone Hosny1; Howayda Abdel-Hamid1; Yasser Ibrahim2
1Internal Medicine Department, Ain Shams University
2Damanhour Medical Institute
Abstract
Fiftypatientswithchronicrenalfailureonregularhemodialysis31malesand19females, agedfrom18to62yearswereincludedinthestudy.Theywereselectedfromthoseattending theNephrologyandDialysisUnitinDamanhourMedicalInstitute.
Tenageandsexmatchedsubjectswithnormalrenalfunctionservedascontrolgroup.Full historytaking,clinicalexamination,restingECGandserumcholesterol,HDL(non-fasting), fastingLDL,non-fastingnon-HDLfromspecialequation,Non-HDL=totalcholesterol-HDL andDuplexscanningofbothcarotidandfemoralarteries.
Nonfastingnon-HDLwasmorethan130mg/dlinmorethan65%ofpatientsgroup versus30%incontrolgroup,serumlevelofnon-fastingcholesterolandnon-fastingnon-HDL weresignificantlyelevatedinhemodialysispatientsascomparedwithcontrolgroup,while serumlevelofnon-fastingHDLandfastingLDLweresignificantlydecreasedinhemodialysis patientsascomparedwithcontrolgroup.Intima-Mediathickness(IMT)ofbothcarotidsand bothfemoralarterieswaselevatedinhemodialysispatientsascomparedwithcontrolgroup. Therewasasignificantpositivecorrelationbetweennon-fastingnon-HDLandIMTofboth carotidsandbothfemoralarteriesandasignificantpositivecorrelationbetweenfastingLDL andIMTofbothcarotidsandfemoralarteries.Therewasasignificantpositivecorrelation betweendurationofdialysisandIMTofbothcarotidsandleftfemoralarteries.
ApositivecorrelationexistsbetweenECGischemicchangesandIMTofbothcarotidsand leftfemoralarteriesandbetweencarotidplaquesandIMTofbothcarotidsandleftfemoral arteries.
Aim of the Work
Tostudyandcomparebetweenthelevelofnon-fastingnon-HDL-CandfastingLDLin predialysisserumaspredictorofatheroscleroticchangesinpatientswithendstagerenaldisease onregularhemodialysis.
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