Copper, Zinc, Selenium, Cadmium and Lead Levels in plasma of Hemodialysis Patients. | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 13, Volume 24, Issue 1, July 2006, Pages 556-563 PDF (237.99 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2006.17923 | ||
| Authors | ||
| Shawkia S. A. El-Sherbeny1; Asmaa, M. Abd Allah2; Waleed Massoud3 | ||
| 1Nutritional Biochemistry Department. National Nutrition Institute | ||
| 2Clinical Nutrition Department. National Nutrition Institute | ||
| 3Nephropathy Department-Ahmed Maher Teaching Hospital. | ||
| Abstract | ||
| Introduction: Hemodialysis patients are at risk of developing trace elements imbalance and increase in heavy metals. Objective: The objective of this study was to asses plasma levels of copper, zinc, selenium, cadmium and lead of hemodialysis patients. Design: The study comprised 40 patients aged 27-65 years under regular hemodialysis for 1.8-13 years and 28 healthy age and sex matched the control. Copper, zinc, selenium, cadmium and lead plasma levels were determined by atomic absorption spectrophotometry. Results: Levels of copper, zinc and selenium were significantly decreased in dialysis patients compared with the control group; the percentage decrease was 25.5%, 20.4% and 19.0% for copper zinc and selenium, respectively. Moreover, cadmium and lead plasma levels showed significant increases among hemodialysis patients versus their matched controls with percentage of 144.6% and 28.1% for cadmium and lead, respectively. Conclusions: Levels of trace elements are altered and heavy metals showed increased plasma levels by hemodialysis. Regular monitoring of trace elements and heavy metals in hemodialytic patients is advisable. | ||
| Keywords | ||
| Hemodialysis; copper; zinc; selenium | ||
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