Effect of Sun Exposure on the Skin: Histological, Histochemical, and Immunohistochemical Studies | ||
| Journal of High Institute of Public Health | ||
| Article 3, Volume 34, Issue 4, October 2004, Pages 763-774 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jhiph.2004.181788 | ||
| Authors | ||
| Safia M. Hassan1; Samar A. Rabah2; A M. Mohsein3 | ||
| 1Department of Histochemistry and Cell Biology, Medical Research Institute, Alexandria University, Egypt | ||
| 2Department of Biology, Faculty of Science, King Abdel-Aziz University Jeddah, Saudi Arabia | ||
| 3Department of Dermatology and Venereology, Faculty of Medicine, Alexandria University, Egypt | ||
| Abstract | ||
| The present work was designed to explore certain aspects concerning human skin in the domain of sun exposure. Skin biopsies were taken from fifteen subjects divided into two groups; chronically sun-exposed group consisted of 10 subjects and control group consists of 5 subjects with no history of chronic sun exposure. Histological signs of sun-damaged skin were prominent as a pronounced thickening of stratum corneum indicating a hyperproliferative state accompanied by a corresponding decrease in collagen content associated with large bundles of coarse abnormal elastic fibers. Depletion of Langerhans immune cells in addition to decreased nuclear DNA was also observed. | ||
| Keywords | ||
| Sun Exposure; Skin | ||
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