EFFECT OF ADMINISTRATION OF A-TOCOPHEROL, NIGELLA SATIVA SEEDS TOGETHER WITH DEEP FRIED FAT ON GLUTATHIONE DEPENDENT ENZYMES AND LIPID PEROXIDES IN RATS LIVER | ||
| Assiut Veterinary Medical Journal | ||
| Article 12, Volume 38.2, Issue 76, January 1998, Pages 151-160 PDF (3.47 M) | ||
| Document Type: Research article | ||
| DOI: 10.21608/avmj.1998.183156 | ||
| Authors | ||
| Evan I. Saad1; Amal A. Rady2; A.A. Mandour2 | ||
| 1Dept. of Pharmacology, Fac. of Pharmacy, Alex. Univ. | ||
| 2Dept. of Biochemistry, Fac. of Vet. Med. Alex. Univ. | ||
| Abstract | ||
| In vivo studies were carried out to decide how vitamin E (dl. a-tocopherol acetate) and Nigella sativa seeds administrated orally combined with or without the deep fat frying (over heated oil) influence the glutathione dependent enzymes [(glutathione peroxidase (GP-ase), Glutathione reductase, (G-R-ase) and Glutathione transferase, (G-S-ase)), as well as reduced glutathione (GSH), Hydroxyl radical (OH) and lipid peroxidation (LP) of rat liver. It was found that, both vit. E and N.sativa seeds influence the action of deep fried fat but they are not able fully to prevent or eliminate its toxic effects. | ||
| Keywords | ||
| Key words: Nigella sativa seeds; c; Tocopherol; Enzymes; Rat liver | ||
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