BINUCLEOPHILIC REACTION IN SYNTHESIS OF PYRIDOPYRROLOPYRAZINES AS POTENTIAL ANTIMICROBIAL AGENTS | ||||
| Zagazig Journal of Pharmaceutical Sciences | ||||
| Article 3, Volume 8, Issue 1, June 1999, Page 15-22 PDF (2.57 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zjps.1999.184161 | ||||
 View on SCiNiTO | ||||
| Author | ||||
El-Sayed Lashine 
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| Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||||
| Abstract | ||||
| Synthesized from dichloromaleimides and 5-bromo -2,3-diaminopyridine as binucleophil, novel pyridopyrrolopyrazines have been described. The synthetic approach involved application of reductive nitrosation reaction recently developed in our laboratories. | ||||
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