BINUCLEOPHILIC REACTION IN SYNTHESIS OF PYRIDOPYRROLOPYRAZINES AS POTENTIAL ANTIMICROBIAL AGENTS | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 3, Volume 8, Issue 1, June 1999, Pages 15-22 PDF (2.57 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.1999.184161 | ||
| Author | ||
| El-Sayed Lashine* | ||
| Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||
| Abstract | ||
| Synthesized from dichloromaleimides and 5-bromo -2,3-diaminopyridine as binucleophil, novel pyridopyrrolopyrazines have been described. The synthetic approach involved application of reductive nitrosation reaction recently developed in our laboratories. | ||
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