SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY
Lashine, E., El-Adl, S., Metwally, K., Abou-Kull, M. (1999). SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY. EKB Journal Management System, 8(1), 23-27. doi: 10.21608/zjps.1999.184162
El-Sayed Lashine; Sobhy El-Adl; Kamel Metwally; Mansour Abou-Kull. "SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY". EKB Journal Management System, 8, 1, 1999, 23-27. doi: 10.21608/zjps.1999.184162
Lashine, E., El-Adl, S., Metwally, K., Abou-Kull, M. (1999). 'SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY', EKB Journal Management System, 8(1), pp. 23-27. doi: 10.21608/zjps.1999.184162
Lashine, E., El-Adl, S., Metwally, K., Abou-Kull, M. SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY. EKB Journal Management System, 1999; 8(1): 23-27. doi: 10.21608/zjps.1999.184162

SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY

Zagazig Journal of Pharmaceutical Sciences
Article 4, Volume 8, Issue 1, June 1999, Pages 23-27    PDF (2.09 M)
Document Type: Original Article
DOI: 10.21608/zjps.1999.184162
Authors
El-Sayed Lashine* 1; Sobhy El-Adl2; Kamel Metwally3; Mansour Abou-Kull4
1Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
2Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt
3Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig. Egypt
4Medicinal Chemistry Department, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt
Abstract
A series of quinolinoxymethyl triazole (5), oxadiazole (6,8), isoxazolidin-3,5-diones (10), pyrazolidin-3,5-diones (11a,b) and other related pyrimidin-2,4,6-triones (12,) and pyrimidin-4,6-dione-2-thiones (12a) were synthesized. Four of the synthesized compounds were tested for antimicrobial activity; two of them displayed high activity against a variety of bacterial strains.
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