SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES | ||
Zagazig Journal of Pharmaceutical Sciences | ||
Article 17, Volume 3, Issue 2, December 1994, Pages 148-152 PDF (1.46 M) | ||
Document Type: Original Article | ||
DOI: 10.21608/zjps.1994.186590 | ||
Author | ||
Gamal Ahmed* | ||
Chemistry Department, Faculty of Science, Zagazig University, Egypt. | ||
Abstract | ||
3-Cyano-4,6-dimethyl-2-pyridinethiol 1 was allowed to react with chloroacetone and hydrazine hydrate to give the corresponding thienopyridine derivative 2 and pyrazolopyridine derivative 5, respectively. Compound 2 reacted with aldehydes to yield 3a-3c. Reaction of compound 5 with thionyl chloride and arylidinemalononitriles gives 6 and 8a,b, respectively. Compound 6 reacted with benzil and p,p-dichlorobenzil to yield the corresponding benzilimine derivatives 7a,b. | ||
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