FORMATION OF A DEXTRAN / B-CYCLODEXTRIN POLYMER BY IMMOBILIZED LEUCONOSTOC MESENTEROIDES IN CALCIUM ALGINATE BEADS | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 8, Volume 3, Issue 1, June 1994, Pages 62-71 PDF (5.55 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.1994.186610 | ||
| Authors | ||
| Abdel-Halim El-Sayed* 1; Robert Coughlin2 | ||
| 1Department of Microbiology, Faculty of Pharmacy, Zagazig University, Egypt | ||
| 2SymBiotech, Inc. and Department of Chemical Engineering, University of Connecticut, Storrs, CT, USA | ||
| Abstract | ||
| Dextran was produced using immobilized cells of L. mesenteroides ATCC 10830 (NRRL SB-512F) in 3% calcium aiginate beads in absence and presence of 1% (w/v) B-cyclodextrin (B-CD). Information about the molecular structure of the produced polymers was obtained using size exclusion chromatography and on-line low angle laser light scattering (SEC/LALLS) detection. Addition of B-CD to the dextran production medium led to a drastic change in the structure of the produced dextran. Branching of the produced polymer in presence of ß-CD was drastically increased and possibly produced a star-like polymer containing B-CD in the center with different dextranyl residues attached to its primary or secondary hydroxyl groups.resolution. | ||
|
Statistics Article View: 90 PDF Download: 141 |
||
