Evaluation Of Transforming Growth Factor (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 14, Volume 7, Issue 1, April 2002, Pages 168-176 PDF (379.87 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2002.18849 | ||
| Authors | ||
| Effat A. Abbas1; Wafaa E. Abdel-Aal2; Aml A. Samy3 | ||
| 1Basic Medical Sciences Department | ||
| 2Medical Division, National | ||
| 3Research Center | ||
| Abstract | ||
| Objective: The present study aimed to investigate the pattern of expression of transforming growth factor & (TGF-&) and epidermal growth factor receptor (EGFR) in oral squamous cell carcinoma (OSCC) and to correlate their expression with tumor grading. Conclusion: This study showed that OSCC express both EGFR and TGF-& and their expression indicated that these markers may have a potential diagnostic value in histologic examination. In addition their increased expression in high tumour grades suggest that they may be used as indicators of tumor aggressiveness. | ||
| Keywords | ||
| Oral squamous cell carcinoma; Epidermal growth factor receptor; transforming growth factor-& and immunohistochemistry | ||
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