SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS
Abou-Kull, M., Lashine, S., El-Shanawani, A., Abou Taleb, N., Amer, M. (1993). SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS. EKB Journal Management System, 2(1), 140-149. doi: 10.21608/zjps.1993.188998
Mansour Abou-Kull; Sayed Lashine; Abdalla El-Shanawani; Nageh Abou Taleb; Magdy Amer. "SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS". EKB Journal Management System, 2, 1, 1993, 140-149. doi: 10.21608/zjps.1993.188998
Abou-Kull, M., Lashine, S., El-Shanawani, A., Abou Taleb, N., Amer, M. (1993). 'SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS', EKB Journal Management System, 2(1), pp. 140-149. doi: 10.21608/zjps.1993.188998
Abou-Kull, M., Lashine, S., El-Shanawani, A., Abou Taleb, N., Amer, M. SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS. EKB Journal Management System, 1993; 2(1): 140-149. doi: 10.21608/zjps.1993.188998

SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS

Zagazig Journal of Pharmaceutical Sciences
Article 14, Volume 2, Issue 1, June 1993, Pages 140-149    PDF (4.43 M)
Document Type: Original Article
DOI: 10.21608/zjps.1993.188998
Authors
Mansour Abou-Kull* 1; Sayed Lashine2; Abdalla El-Shanawani3; Nageh Abou Taleb4; Magdy Amer5
1Medicinal Chemistry Department, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt
2Pharmaceutical Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt
3Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
4FACULTY OF PHARMACY, CAIRO UNIVERSITY
5Department of Pharmacology, Faculty of Veterinary Medicine, University of Mansoura, Egypt.
Abstract
A series of N - 3 - chloro -N- substituted phenyl -2- maleimidyl  anthranilic acid and its methyl ester were prepared. The reaction of either IV or V with potassium thiocyanate afforded quinazolinone thione derivatives. four of the prepared new compounds were screened pharmacologically for their antiinflammatory, analgesic and antipyretic properties.
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