PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).
ABD EL-AZIZ, M., El-Sheikh, S., Shams, G., Abdel Fadil, H., ABDEL ALIM, A., MALHAT, S. (1992). PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).. EKB Journal Management System, 1(2), 103-119. doi: 10.21608/zjps.1992.189012
MOSTAFA ABD EL-AZIZ; Sawsan El-Sheikh; Gamal Shams; Hosny Abdel Fadil; A.F. ABDEL ALIM; S.M. MALHAT. "PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).". EKB Journal Management System, 1, 2, 1992, 103-119. doi: 10.21608/zjps.1992.189012
ABD EL-AZIZ, M., El-Sheikh, S., Shams, G., Abdel Fadil, H., ABDEL ALIM, A., MALHAT, S. (1992). 'PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).', EKB Journal Management System, 1(2), pp. 103-119. doi: 10.21608/zjps.1992.189012
ABD EL-AZIZ, M., El-Sheikh, S., Shams, G., Abdel Fadil, H., ABDEL ALIM, A., MALHAT, S. PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).. EKB Journal Management System, 1992; 1(2): 103-119. doi: 10.21608/zjps.1992.189012

PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).

Zagazig Journal of Pharmaceutical Sciences
Article 3, Volume 1, Issue 2, December 1992, Pages 103-119    PDF (7.92 M)
Document Type: Original Article
DOI: 10.21608/zjps.1992.189012
Authors
MOSTAFA ABD EL-AZIZ* 1; Sawsan El-Sheikh2; Gamal Shams3; Hosny Abdel Fadil1; A.F. ABDEL ALIM1; S.M. MALHAT1
1Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.
2Department of Pharmacology, Faculty of Vet. Medicine, Zagazig University
3Pharmacology Department, Faculty of Vet. Med., Zagazig University, Egypt
Abstract
A relaxant effect was achieved by praziquantel on the rat thoracic aortic strip preparations which might be of cholinergic nature.
Praziquantel produced an acetylcholine-like effect on the perfused rabbit's heart.
A transient hypotensive effect and respiratory depression and altered ECG were traced. These effects revealed the peripheral cholinergic effects of the drug.
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