Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients | ||
| Zagazig University Medical Journal | ||
| Article 816, Volume 30, Issue 3, May and June 2024, Pages 1021-1027 PDF (342.42 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2021.79462.2256 | ||
| Authors | ||
| Lobna Salem* 1; Amin Amer2; Abdulla Esawy3 | ||
| 1Department of dermatology, faculty of medicine, Zagazig university, Egypt | ||
| 2Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University | ||
| 3Department of of Dermatology, Venereology and Andrology, Faculty of Medicine - Zagazig University. | ||
| Abstract | ||
| Chronic kidney disease-associated pruritus (CKD-AP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It remains one of the most tormenting, frequent, and potentially disabling problems in patients with an advanced or end-stage renal disease who are on dialysis including peritoneal dialysis and hemodialysis. Omega-3 fatty acids are increasingly being used for their clinical benefits some of which are relevant to individuals with advanced CKD. It was found to be a safe drug that has other benefits on uremic pruritis such as reducing cholesterol, triglycerides, LDL, blood pressure, atherosclerosis, and oxidative stress. Patient ad methods: This study was performed as a randomized, clinical trial study on 36 patients under hemodialysis three times a week, for 4 hours each session to assess the effects of Omega-3 fatty acids for treatment of pruritis in hemodialysis patients. Conclusion: Omega-3 fatty acids was found to be a safe drug and achieved a high therapeutic response with a reasonable cost that is maintained for a relatively long period. In addition to reducing cholesterol, triglycerides, blood pressure, atherosclerosis, and oxidative stress | ||
| Keywords | ||
| pruritus; CKD; itching; Omega-3 fatty acids | ||
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