An Improved Sensitive and Selective Non-enzymatic Glucose Biosensor Based on PEG Assisted CuO Nanocomposites | ||
| Egyptian Journal of Chemistry | ||
| Article 9, Volume 62, Issue 3, March 2019, Pages 487-500 PDF (3.43 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2018.5707.1489 | ||
| Authors | ||
| AbdulSalam Mohamed Azharudeen1; Thevaraj Suriyakala1; Muthuramalingam Rajarajan* 2; Ayyadurai Suganthi3 | ||
| 1Department of Chemistry C.P.A. College, Bodinayakanur, Theni District, TamilNadu. | ||
| 2Department of Chemistry, Madurai Kamaraj University, Madurai-625021. TamilNadu, India. | ||
| 3Mother Teresa Women's University, Kodaikanal, Dindugal District. TamilNadu. | ||
| Abstract | ||
| Determination of glucose is of enormous importance in the fields of biological, environmental and clinical analyses. In recent years, polymer modified metal oxides arrived a great consideration in the detection of glucose. In this study, we have developed a sensitive and selective non-enzymatic glucose sensor by using CuO NMO encapsulation with PEG (poly ethyleneglycol) nanocomposites. The loading content of PEG was incorporated with CuO by weight percentage (wt = 2, 4 & 6%). The fabricated CuO/PEG nanocomposites was utilized as a glucose sensor, it exhibit the tremendous electrocatalytic performances on oxidation of glucose. The electrocatalytic activity enhances with increasing the loading of PEG content. The sensor shows a low detection limit of 0.25 µM with a sensitivity of 113.8 µA mM-1 cm-2, good selectivity and stability. The CuO/PEG nanocomposites are hopeful for the advancement of cost-effective non-enzymatic glucose biosensors. | ||
| Keywords | ||
| CuO; Mesoporous; PEG; glucose; Biosensor | ||
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