Green-synthesis of Platinum Nanoparticles using Olive Leaves Extracts and its Effect on Aspartate Aminotransferase Activity | ||
| Egyptian Journal of Chemistry | ||
| Article 37, Volume 65, Issue 4, April 2022, Pages 377-382 PDF (594.51 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.91747.4355 | ||
| Authors | ||
| Srwa Hashim Mohammed1; Ahmed Rheima* 2; Firas Al-jaafari3; Mohammed F. Al-Marjani4; zainab abbas5 | ||
| 1Department of Chemistry, College of education, University of garmian, Kalar, Iraq | ||
| 2Chemistry department, science college, Wasit university, Al Kut Iraq | ||
| 3Physics Department, College of Science, Wasit University, Kut, Iraq | ||
| 4Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq | ||
| 5Department of Dentistry, Kut University College, Kut, Wasit , Iraq | ||
| Abstract | ||
| This study aims to synthesize Platinum nanoparticles (Pt NPs) using Olive leaves extract's environmentally friendly approach. UV-Visible spectroscopy has been used to follow the turning of Pt +4 ions to Pt0 NPs. X-ray diffraction (XRD) has been used to investigate the as-synthesized Pt NPs and its cubic face-centered structure crystallinity. The average size of nanoparticles was 9.2 nm, calculated by transmission electron microscopy (TEM). The activity of as-synthesized Pt NPs has been examined by inhibition of Serum Aspartate Aminotransferase (AST) level in patients with chronic liver disease and control group, The AST (mean= 12.8051.642) demonstrate a very significant rise (p < 0.01) in the results. In chronic liver patients with Pt NPs, serum AST activity was significantly lower (p < 0.01) than in patients without Pt NPs (mean=13.4582.360). The present study concluded that Platinum nanoparticles play a great role in inhibition of AST. | ||
| Keywords | ||
| Platinum nanoparticles; Olive leaves extract; TEM; AST | ||
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