Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives
A Wani, M., A Farooqi, J., A Shah, W. (2016). Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives. EKB Journal Management System, 2(2), 89-93. doi: 10.18576/jpac/020204
Mukhtar A Wani; Javeed A Farooqi; Wajahat A Shah. "Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives". EKB Journal Management System, 2, 2, 2016, 89-93. doi: 10.18576/jpac/020204
A Wani, M., A Farooqi, J., A Shah, W. (2016). 'Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives', EKB Journal Management System, 2(2), pp. 89-93. doi: 10.18576/jpac/020204
A Wani, M., A Farooqi, J., A Shah, W. Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives. EKB Journal Management System, 2016; 2(2): 89-93. doi: 10.18576/jpac/020204

Synthesis and Antimicrobial Activity of Some Furfural Substituted Bisdimedone Derivatives

Journal of Pharmaceutical and Applied Chemistry
Volume 2, Issue 2, May 2016, Pages 89-93    PDF (189.88 K)
Document Type: Original Article
DOI: 10.18576/jpac/020204
Authors
Mukhtar A Wani1; Javeed A Farooqi1; Wajahat A Shah2
1IGNOU New Delhi, India
2University of Kashmir, India
Abstract
Bisdimedone derivatives were synthesized by the method adopted by Horning and Honing. All the newly synthesized compounds showed antimicrobial activities against certain bacterial and fungal strains. The compounds 2-(2-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran and 2-(4-flor-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)methylfuran showed good activity against Proteus mirabilis and Klebsiella pneumonia and 2-(4-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran and 2-(2-chloro-phenyl)-5-bis(1,3diketo-5,5-dimethyl cyclohexyl)-methylfuran showed prominant activity against Staphylococcus aureus. Bisdimedone derivatives shows fungicide activity as well.

Keywords
bisdimedone; antimicrobial activity; fungicide xanthenes
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