Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients
El-din, M., Kany, A., Massoud, E., El-Agamawi, A., Ezz El-din, M. (2021). Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients. EKB Journal Management System, 2021(12), 23-31. doi: 10.21608/absb.2021.93331.1133
Maged M. E. El-din; Amr M. Kany; Eman Massoud; Ahmed Y. El-Agamawi; Mohamed R. Ezz El-din. "Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients". EKB Journal Management System, 2021, 12, 2021, 23-31. doi: 10.21608/absb.2021.93331.1133
El-din, M., Kany, A., Massoud, E., El-Agamawi, A., Ezz El-din, M. (2021). 'Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients', EKB Journal Management System, 2021(12), pp. 23-31. doi: 10.21608/absb.2021.93331.1133
El-din, M., Kany, A., Massoud, E., El-Agamawi, A., Ezz El-din, M. Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients. EKB Journal Management System, 2021; 2021(12): 23-31. doi: 10.21608/absb.2021.93331.1133

Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients

Al-Azhar Bulletin of Science
Article 6, Volume 2021, Issue 12, December 2021, Page 23-31  XML PDF (619.14 K)
Document Type: Original Article
DOI: 10.21608/absb.2021.93331.1133
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Authors
Maged M. E. El-din email 1; Amr M. Kany2; Eman Massoud3; Ahmed Y. El-Agamawi4; Mohamed R. Ezz El-din1
1Radiation Protection Department, Egyptian Nuclear and Radiological Regulatory Authority, Cairo, Egypt.
2Faculty of science Al-Azhar University, Cairo, Egypt.
3Jeddah International College, Jeddah, Saudi Arabia.
4Faculty of medicine Al-Azhar University, Cairo, Egypt.
Abstract
During radiotheranostic procedures, radioiodine-131(131I)activities deliver high internal gamma (ɣ) doses to the patient’s organs. Thus, studying the internaldoses of patients is highly required to predict the stochastic or deterministiceffect of gamma radiation that may occur to patients.The objective ofthis study is to calculatethe internal doses for 11 critical organs or body tissues insideWell Differentiated Thyroid Cancer (WDTC) patients’ bodiesafter receiving diagnostic and therapeutic 131I activitiesorally during 6days post administration.Internal effective doses delivered tocritical organs are estimated mathematically using Monte Carlo simulation model in which the actual geometry, volume, mass of organs and the source localization wasdesigned based onthe patients’ CT images and Oak Ridge National Laboratory (ORNL) phantom.Thus, an average sized human phantom was constructed using MCNP5in whichtwo 131I sources were distributed in the abdominal and the thyroid gland sections.No significant radiation effect is expected during diagnostic procedures for the investigated organs including the thyroid itself. However,some deterministic effects or induction of thyroid cancer might be observedfor patients undergoing postoperative radiotherapy with largeprescribed activities.             
Keywords
Radioiodine-131; Internal Dosimetry; Monte Carlo; Well Differentiated Thyroid Cancer
References
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