Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols
Madboly, M., Khater, M., Almassry, H., Zaiton, F., Hassanin, A. (2021). Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols. EKB Journal Management System, 85(2), 4028-4034. doi: 10.21608/ejhm.2021.207084
Marwa Hassan Madboly; Mohamed Fathy Khater; Hosam N. Almassry; Fatma Zaiton; Ali M. Hassanin. "Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols". EKB Journal Management System, 85, 2, 2021, 4028-4034. doi: 10.21608/ejhm.2021.207084
Madboly, M., Khater, M., Almassry, H., Zaiton, F., Hassanin, A. (2021). 'Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols', EKB Journal Management System, 85(2), pp. 4028-4034. doi: 10.21608/ejhm.2021.207084
Madboly, M., Khater, M., Almassry, H., Zaiton, F., Hassanin, A. Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols. EKB Journal Management System, 2021; 85(2): 4028-4034. doi: 10.21608/ejhm.2021.207084

Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols

The Egyptian Journal of Hospital Medicine
Article 98, Volume 85, Issue 2, October 2021, Page 4028-4034  XML PDF (959.13 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2021.207084
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Authors
Marwa Hassan Madboly email ; Mohamed Fathy Khater; Hosam N. Almassry; Fatma Zaiton; Ali M. Hassanin
Abstract
Background: End-Stage Renal Disease (ESRD) patients on hemodialysis suffered from many central and peripheral neurological insults. Aim of the work:This study aimed to assess the value of using MRA, MRV, and SWAN sequences in early visualization of the silent cerebrovascular complications in those patients.
Patients and Methods: Our study was conducted on forty-five patients with well-documented ESRD on regular hemodialysis for more than 5 years with no neurological manifestation, all undergone unenhanced MRI, DWI with ADC and measuring the ADC value, SWAN, MRA, and MRV.
Results: we found that 11% of cases have acute infarction at the basal ganglia region. 36.7% of patients are diagnosed with intracerebral hemorrhage, only 26.7% of them are seen by the conventional MRI, and 16.7% of cases showed microbleeds on SWAN with normal conventional MRI. The sensitivity and specificity of SWAN with ADC value to detect brain hemorrhage are 100% and 88.8% respectively.
Conclusion: Visualization of cerebrovascular complications such as infarction, hemorrhage, atherosclerosis, and arterial and venous occlusion using DWI with ADC, MRA, MRV, and SWAN and is very useful in early management and better prognosis of ESRD patients even with silent complications that don’t give up symptoms with high sensitivity and specificity of SWAN in early detection of hemorrhage and microbleeds.
 
Keywords
Cerebrovascular; Hemodialysis; DWI; MRI
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