HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS
El-Shouny, F., El-Kadousy, S., El-Gawad, S., El-Khalwy, K. (2021). HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS. EKB Journal Management System, 6(6), 57-69. doi: 10.21608/mjab.2021.207624
F. M. El-Shouny; S. K. El-Kadousy; S. M. El-Gawad; Kh. A. El-Khalwy. "HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS". EKB Journal Management System, 6, 6, 2021, 57-69. doi: 10.21608/mjab.2021.207624
El-Shouny, F., El-Kadousy, S., El-Gawad, S., El-Khalwy, K. (2021). 'HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS', EKB Journal Management System, 6(6), pp. 57-69. doi: 10.21608/mjab.2021.207624
El-Shouny, F., El-Kadousy, S., El-Gawad, S., El-Khalwy, K. HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS. EKB Journal Management System, 2021; 6(6): 57-69. doi: 10.21608/mjab.2021.207624

HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS

Menoufia Journal of Agricultural Biotechnology
Article 3, Volume 6, Issue 6, November 2021, Page 57-69  XML PDF (601.43 K)
Document Type: original papers
DOI: 10.21608/mjab.2021.207624
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Authors
F. M. El-Shouny; S. K. El-Kadousy; S. M. El-Gawad; Kh. A. El-Khalwy
Biochemistry- Dep., Faculty of Agricultural, Menoufia University
Abstract
Chemical composition of milk thistle seed flour )MTSF) and turmeric (T) were investigated, for milk thistle seed flour,  moisture (8.0%), protein (13.0 %), carbohydrates (27.55%), crude lipid (15.0%), ash (10.45%), and crude fiber (26.0%), while turmeric has moisture (8.1%) ,  protein (9.3 %), carbohydrates (57%), crude lipid (17.0%), ash (6.0%) and crude fiber (2.6%). For total phenol, the highest value in turmeric (11.57mg GAE/g) while milk thistle seed flour (3.39 mg GAE/g)) also total flavonoid for turmeric (4.9mg) while and in milk thistle seed flour (2.34mg). DPPH for milk thistle recorded the highest percent of (FRSA) 98.5 % and turmeric recorded lowest present 82.2% in concentration 100 µg/ml. Reducing power for milk thistle recorded 0.651 but turmeric (T) recorded 0.502 in concentration 100 µg/ml . The identification of phenolic compounds for plant extracts were investigated by HPLC ,the highest content in milk thistle seed flour (MTSF) was Benzoic acid (103.33 ppm) while the lowest content was Caffeine(1.07 ppm) but in turmeric(T) the highest content was Benzoic acid (208.41 ppm), while the lowest content was quercitin (3.08 ppm).The level of plasma aspartate aminotransferase (AST) , alanine aminotransferase (ALT) , alkaline phosphatase (ALP) , total bilirubin , total protein and albumin and plasma antioxidant state SOD , CAT, GPx and MDA were determined to assay hepatotoxicity.
Keywords
Milk thistle seed flour; disorder; Biochemical analyss
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