Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids
Al–Farhan, B., Gahlan, A., Haredy, A., Fraghly, O. (2022). Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids. EKB Journal Management System, 65(7), 421-428. doi: 10.21608/ejchem.2021.104642.4835
Badriah Saad Al–Farhan; Ahmed A. Gahlan; Ahmed M. Haredy; Othman A. Fraghly. "Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids". EKB Journal Management System, 65, 7, 2022, 421-428. doi: 10.21608/ejchem.2021.104642.4835
Al–Farhan, B., Gahlan, A., Haredy, A., Fraghly, O. (2022). 'Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids', EKB Journal Management System, 65(7), pp. 421-428. doi: 10.21608/ejchem.2021.104642.4835
Al–Farhan, B., Gahlan, A., Haredy, A., Fraghly, O. Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids. EKB Journal Management System, 2022; 65(7): 421-428. doi: 10.21608/ejchem.2021.104642.4835

Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids

Egyptian Journal of Chemistry
Article 41, Volume 65, Issue 7, July 2022, Page 421-428  XML PDF (438.49 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.104642.4835
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Authors
Badriah Saad Al–Farhan1; Ahmed A. Gahlanorcid 2; Ahmed M. Haredy email orcid 3; Othman A. Fraghly2, 4
1Chemistry Department, Faculty of Girls for Science, King Khalid University, Abha, Kingdom of Saudi Arabia
2Chemistry Department, Faculty of Science, Al –Azhar University, Assiut Branch, 71524, Assiut, Egypt
3Pharmaceutical Analytical Department, Faculty of Pharmacy, Merit University, New Sohag, Egypt
4Chemistry Department, Faculty of Science, Al Baha University, Al Baha, Kingdom of Saudi Arabia
Abstract
Lisinopril (LSP) in pharmaceutical dosage forms and biological fluids was studied using the square wave cathodic stripping voltammetric method (SWCSV) at a carbon paste electrode (CPE). To maximize the method's circumstances, many parameters were defined. The linear concentration range of 3.53 – 44.17 ng/mL was effectively determined at ideal conditions of 0.08 M Britton-Robinson buffers (pH = 9.00) at accumulation times 15, 30 sec., and 2.64 – 44.17 ng/mL at 60 sec. With good results, the standard addition method was employed to determine LSP in pure solutions, tablets, and biological fluids. The proposed method is compared to the previously published standard method.
Keywords
Lisinopril, Cathodic Stripping Voltammetric, Dosage Forms; Biological Fluids
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