Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma
Fahmy, H., Ali, A., Sayed, S., Sayed, M. (2022). Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma. EKB Journal Management System, 42(1), 27-38. doi: 10.21608/besps.2021.71460.1100
hassan Lotfy Fahmy; Anwar Mohammed Ali; Sally Anwar Sayed; Mohammed Anwar Sayed. "Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma". EKB Journal Management System, 42, 1, 2022, 27-38. doi: 10.21608/besps.2021.71460.1100
Fahmy, H., Ali, A., Sayed, S., Sayed, M. (2022). 'Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma', EKB Journal Management System, 42(1), pp. 27-38. doi: 10.21608/besps.2021.71460.1100
Fahmy, H., Ali, A., Sayed, S., Sayed, M. Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma. EKB Journal Management System, 2022; 42(1): 27-38. doi: 10.21608/besps.2021.71460.1100

Correlation between serum 25-hydroxyvitamin D levels and VEP and OCT in patients with primary open-angle glaucoma

Bulletin of Egyptian Society for Physiological Sciences
Article 3, Volume 42, Issue 1, January 2022, Page 27-38  XML PDF (413.78 K)
Document Type: Original Article
DOI: 10.21608/besps.2021.71460.1100
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Authors
hassan Lotfy Fahmy1; Anwar Mohammed Ali2; Sally Anwar Sayed email 3; Mohammed Anwar Sayed1
1Department of Ophthalmology, Faculty of Medicine, Assiut University Hospital, Assiut, Egypt.
2Department of Neurology, Faculty of Medicine, Assiut University Hospital, Assiut, Egypt.
3Department of physiology, Faculty of Medicine, Assiut University
Abstract
Purpose:
Primary open-angle glaucoma has been identified as the most common type of glaucoma. Elevated intraocular pressure, advanced age, positive family history, and African ancestry are well-known risk factors for primary open-angle glaucoma. Vitamin D is a known vital contributor to health. Thus, this present study aimed to clarify the neurophysiological role of vitamin D deficiency in primary open-angle glaucoma and to examine the correlation between vitamin D deficiency and the structural changes associated with primary open-angle glaucoma.
Patients and Methods:
All patients participating in this study underwent the best visual acuity examination. In addition, intraocular pressure, optical coherence tomography, and visual evoked potentials were measured.
Results:
As per our findings, it was determined that vitamin D negatively correlated with intraocular pressure in patients less than 45 years of age (r-value: −0.803; p-value: 0.002). Vitamin D also negatively correlated with age when optical coherence tomography was >94 µm (r-value: −0.526; p-value: 0.044). Vitamin D negatively correlated with intraocular pressure when visual evoked potential latency was Conclusion:
We can conclude that vitamin D has an ameliorating effect on intraocular pressure when optic nerve conduction velocity is normal, but once optic nerve function deteriorates, the vitamin D effect decreases.
Keywords
Primary open-angle glaucoma; Vitamin D; IOP; OCT; VEP
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