Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes
Vijayabaskaran, S., B., D., Damodaran, V., Nagarajan, S. (2022). Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes. EKB Journal Management System, 14(1), 21-30. doi: 10.21608/eajbsc.2022.213921
S. Vijayabaskaran; Dhanashree. B.; V. Damodaran; S. Nagarajan. "Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes". EKB Journal Management System, 14, 1, 2022, 21-30. doi: 10.21608/eajbsc.2022.213921
Vijayabaskaran, S., B., D., Damodaran, V., Nagarajan, S. (2022). 'Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes', EKB Journal Management System, 14(1), pp. 21-30. doi: 10.21608/eajbsc.2022.213921
Vijayabaskaran, S., B., D., Damodaran, V., Nagarajan, S. Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes. EKB Journal Management System, 2022; 14(1): 21-30. doi: 10.21608/eajbsc.2022.213921

Association between Lipid Levels and Short-Term Heart Rate Variability (HRV) In Type 2 Diabetes

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Article 3, Volume 14, Issue 1, June 2022, Page 21-30  XML PDF (761.21 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2022.213921
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Authors
S. Vijayabaskaranorcid 1; Dhanashree. B.2; V. Damodaran3; S. Nagarajan4
1Department of Physiology, PSG Institute of Medical Sciences and Research, Peelamedu, Coimbatore, Tamil Nadu, India – 641004
2PSG Institute of Medical Sciences and Research, Peelamedu, Coimbatore, Tamil Nadu, India – 641004.
3MD (Community medicine) PGDHP, Institute of Community Medicine, Madras Medical College, Chennai – 600003
4MS (ENT) (AIIMS), FRCS (Eng), FRCS (Ed), OT ENT Centre, R S Puram, Coimbatore – 641002.
Abstract
Background: There are plenty of studies available to demonstrate the effect of diabetes on short-term Heart Rate Variability (HRV) but not enough about lipids, especially in our region. Hence, we aimed to study the influence of total cholesterol and individual lipid fractions on short-term HRV in type 2 diabetics.
Methods: As per the set criteria, 70 newly diagnosed type 2 diabetics were recruited and grouped based on their cholesterol levels. Both the time domain and the frequency domain measures of short-term HRV were acquired and subjected to statistical analysis. This was a cross-sectional observational study.
Results: Elevated total cholesterol group showed a reduction in Standard deviation of all NN intervals (SDNN) and High Frequency (HF) power and an increase in Low-Frequency power / High-Frequency power (LF/HF) ratio in comparative analysis. Similarly, the high low-density lipoproteins (LDL) group showed a decrease in square root of the mean of the sum of the squares of the differences between adjacent NN intervals (SDNN) and RMSSD but a rise in LF/HF ratio. Moreover, total cholesterol is negatively correlated with SDNN, RMSSD, and HF power while total cholesterol and LDL are positively correlated with LF/HF ratio. Total cholesterol, LDL, and triglycerides had an independent association with HF.
Conclusions: Our study shows higher levels of total cholesterol, LDL and triglycerides decrease cardiovagal activity. Hence, based on this we conclude abnormal lipid levels depress HRV
Keywords
HRV; lipids; total cholesterol; LDL; triglycerides
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